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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1f2d74aaad0f7283b6b05c448e816ac36ef649a1f29dde2f8b0729f46bea860c' 
  AND token = 'a4Txt9ncWe7SZdoGyFVWTXg11873Hg3U6+QuYfgVcS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}