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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a80d7ea79152d92201faf934ca23336434321948009c565a54b3dd9164775272' 
  AND token = 'YHuoeFeI1N/U4C8CpdD7WNgS8KIZNc+t/2cAfBWGQQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}