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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3c83272843d5930e929a89f91ac83ecb94965f1c149970a45e9beddee8469b5b' 
  AND token = 'dWw2ePLnNxOk7MiTnns/gO38zo6xIL/aMuvc7L6UiH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}