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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '579f8389ba5782ac0b11bc8330c9b189f6cc8ee38848d389486db428514c1579' 
  AND token = '+U52l3SXd6iLXrMo9/x68p1HwWTyjqyFISreQ+o9EQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}