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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e3c9f70c137ee5fe767515faa31bb44c47afb33b5bc5279c55a0e1585a050a98' 
  AND token = 'MMxWQV6ntbVjfCZYBkrYNh/ANTqbgNiBY8ujiBuRuZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}