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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '645fcb3968cc343835d4e9c36fdd41c98fc6d8ea827fde98a4c6913b044807be' 
  AND token = 'tLmB+eaatOM4+A8UBCF7f6lDyP9CUvUS4+Q0bS2Z0BU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}