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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '49b3da20757dbbebe131a75cd8415e1199a5b08d4195819eddc7459b16dc199c' 
  AND token = '4nDJoNMnDT+I/TsMkZZJeh0vKQRHKr8Zr+24Xjc3JOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}