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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9ae89dab7bbb8981c3903790ee3da842a1241d33853f90a9af0f20270a32b41e' 
  AND token = 'aS6R6V3iqa9v5fZxYFu+XHVB4RB0/gNvrHYrIH3Rn7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}