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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6f076bc4a9fb121dc763bd87c605a2ea1affaf9cdb9dc6f528bf5195adaa85c3' 
  AND token = 'Ajjff2aSKbp9+c+T9bqQlp5SMeeybHQpuoRD08qmuqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}