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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3f378926dafd92917dac51ba91b8443df1119e41627a6e0030503e99e77e20da' 
  AND token = 'oBPB1MrJbaV4WITXQxCHmqdMMvw2JqMOMo/PLSeuUsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}