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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ef9a341b99519c96ae81630128312c45ef876d6c4d9af99b399c8715ecf9aa27' 
  AND token = 'x6Y1rEN2AbCLLIkeabFxFTCD/2mMuDJXUweU9OFEq9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}