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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '07de5a96cc99fae1ee0e5af5f6d09f8c04a13d1ceffdd490115c25c412da07c5' 
  AND token = 'VlFx4l6OnnI/XwR1co8hjeGiGUlII4VUb9gAQaE8+IM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}