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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '97ed3e2aedc8227ea186e8ac6e88eaff9764cbe2e39727ad146c925539ab10d5' 
  AND token = 'sBbi6MB87t4Q4EgmXk6PvSOI1CkwlBbm+EUCMI/k/Jw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}