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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e3a064ea01689532af166653f8843a6dcc9ca8da114536e77bf0662363b09597' 
  AND token = 'axTBIgHImth75cgpFceW5yAtViNhcPPp9BfoypO7Hhc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}