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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '441ce2f889c179a55f1fa8da16ce02f7f61cb52aaa6abe277544f2ad11cbc2f3' 
  AND token = 'EsVFLTUXV4D6XnUiH6Cj6BaV4e6nKQzTwsQ90qWBy0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}