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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '78ef56afe5dc82fec4ee363c565b99e233e06a0157fbda33901e93d709ac3490' 
  AND token = 'M80SLU2DbkSFdyhNoxfgwqkCqMnw3LGPTnnBRUVEMOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}