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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ce46d953eceaa8e6503e0904e98ec05dc5c495ce557c97a0d2d7259339c5a38b' 
  AND token = '+KoYX0hTq5Ejn/Cq0+T/hVgGYe8E2eTMhWoZ8hFaY1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}