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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '288a408f69d5ff7b3e18f060c16beebe628e6ab6c85e803a1d75ba659e2771ad' 
  AND token = 'ZrfxT9WUhjJCcE/eIYX0HKMhWaioUnmAUQL3XFT46eI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}