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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5041e41a0c5314d68890c0ba384610a66efe0c89c49ce16d1b4981ca93352e05' 
  AND token = 'aHEkwAfuLTRX/VQv9Zw/KQr2wbyPZEiFoSMGgM2IALk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}