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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '66b5fef5a9435b33d364a8c53663e4a2645caa5c603afa2fade7183133dcc87c' 
  AND token = 'X+mDe/XxpkcKWTwMj3iQxwP30vnk+X4AYufUwGyT5OI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}