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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e5d29ecd3e5adbcb084f69bd732486564015cb972ba9e697a2b9461ed0c1c09f' 
  AND token = 'O5uuvfysuHBTvei+g+OSPdT5GXgCc5WnCz6H8aITrcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}