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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '53f1021c86f8b0d4161e2530d7550426c41daa4ba891d717c88d73d5896ea183' 
  AND token = 'eilNWd6ipvR2UfVhrLoXaoKLB5TDXxFi3z8MXf56LFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}