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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '80589deb46da2a530df31a61d8de736c908e3bc41d1cd110d4501ca82b8c7d46' 
  AND token = 'B8Y+I0TMdJPviQ1OLRAt3r4IckYckO/JQ7SCAfzgwug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}