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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '181e61902a39e44c824c9811ecb76a1ad9ddbdf47deec3200beae0b8a61f9c07' 
  AND token = 'YAenrzYvPlru9qcuKA/PxIRSfnhIOW866Hh1SJoy/Q0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}