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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '30bcdab256c0924068f6bdbec5e089677036e693e3274e3ce7a872213e1a4550' 
  AND token = '49gGeYSyGMbTwetooDE77+SLLhKgy5MRu6eu+96Y5Og=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}