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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9421c252f8072568407398a646943033afdcf0533d070b95f7865de3c6749817' 
  AND token = '3QYq2Men3XqLzT6zVVK7MB19z5fc7EHUHx3z23967u4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}