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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b2780e0627c727aa9a15f64844b94f8b1e6022b7a160d2a5e3369ea74593e4ea' 
  AND token = 'mPruWEYqV0tJp7R/x/DFfle41tq5HiJfnbmDv6eZXB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}