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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6618f24d0cfb7a28f59b10e5f3a78ed27a6d610b119223c15f9a01bd5ff77686' 
  AND token = 'JEMSHooTc0kj5d8klYRdatgMGjOuO01wlgtPD3U+UN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}