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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'efe5ae172e335df1e8c446d84d161aef08a9808f7e9c0dad100cb4e978f3cb2b' 
  AND token = 'smh5pliANqqh4grFlgKDb1CO0nQE9sKkpYdMxAILv6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}