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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '43226b1874ff9c027c23011430391861e8b151d664c7876370ac8a4068ce46be' 
  AND token = 'c2IcW8ODvwCSIFv9XULhsEP77IGMrz4/p139dBWyFuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}