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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '78f69aca738043f0707a41865e138c88082ca3154173be01b40b59245de61617' 
  AND token = 'oSyMnmcAaz3o18+ejbfMKkHGHC2tF/d2vfmosnc6SNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}