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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'df15f5d860e6c88cc62f08b18b19a9c46965edfe3bfd809624dc598e9dbbe498' 
  AND token = 'Ys8nw3oADpj6eOyI7apr1J5UZEbiDq7Iv0ox4AdD5s8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}