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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3b61418931b1c31cf6fcb59ab989d50d16b08c4331de3aa4e4169df565dbd6fe' 
  AND token = 'PWlfA65KHO/1INRVlWvBgqXjD9m21i+EQ3JbRS1Cv+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}