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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '49d24554bc0ed440c3820a9670afd44a26ebedad095cb42c823e0077327da378' 
  AND token = 'Y1iUEJfHLgWDKcRkSxKpNFIKm67qIFFoTB4/Nmhl4d0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}