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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7c10c4bc50467825071deb139dd9971029d659598119bd8a1bdeff0797350ace' 
  AND token = 'u6sm0frxsQj1eCh4MI36LAUnanVEKhEuBnoo8a100GI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}