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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8b03e61bda23c55d5dd3dac72997c21b9a524695e12ac20863d89f381948e92b' 
  AND token = 'KHCZjTIczXUbypUOtyT/l8HRGsavjUl32h1beWairYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}