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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '00c3c39d72e182c81c4947dedc0b36382d06ca05fc08a413f619d1da1fc090e2' 
  AND token = 'fFxQBPsYzFf21kQz8A7yyp8GcvkloyoaDrtDAhzL70A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}