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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '189d32ac85983dfbefa2e3c1016c0c418ca08d1a6eaba0ac7bcd9c85906929e3' 
  AND token = '298+75V+5rhNuGCoqLt6aQfTv0y9//vnL6c2TH2KX28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}