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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9453aed648d19279b1ccf3f6bb03f794f5adba093a9f9792f076c02204c2f1c8' 
  AND token = 'LOP7HSu45Jamu5MhNMuzsIBrm68p5swWI7f1w8wAeSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}