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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5a63651a0ee72ff953f5faedf5f963780b10c990c9361302445d22159e50c2dd' 
  AND token = 'tEKSC6xUW6XW8FYEDD4L3d3BiaJKhH7ByeuRsnEgqUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}