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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '80f35e10e80aeca36e32c96a70220dbe1f74fc0803db84d9c67ba37610c94477' 
  AND token = '3Ap2GRtt2DW4NUaWUn8U8XGhtZFk54X9SLEQRcRCZRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}