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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0d0a59f863f72ab0f17b0916153d55e24455d96335cca659a39243373dfef5dd' 
  AND token = 'JQTsdpO+YqWhX1P2+ayY1uhrTRK62rBq7ekU1hCWMiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}