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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a2aee69e9357196548612320a1a7736f99ec7e1746f525af98c77ef344c39121' 
  AND token = 'GxfPY23w0E6HrVMdD2xFPDeeNIBX7mXaeyBGLgGla4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}