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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7d3e6f76ba0e4c359a030cf1c70044a1b0986fd81426b06977561abd0b5e2766' 
  AND token = 'D3WfNArbXODjdBk+nYAk48xGtIZd/alifIHRRSt36do=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}