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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2553d01440dd270f69fc33522caae54930dbdc3a6ff8722a8ac5361e315cbb27' 
  AND token = '0Q3KyOFKkldDNCQstyszA/oFpaR1+7daZF2bk867278=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}