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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '674764420fffa23f29feb8ae3627eacf8053e3d8bf89a09a23ecbba7411845e2' 
  AND token = 'EuTzGMf0GhEpXe7sAOHr9MhJuaadS/IPYZyy3HpyeaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}