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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5b793b492dcc62c029559fe2541caf5c5a5693d50c45cae37d09c50599fa0af9' 
  AND token = 'aGr68qZ2A5iIQ3cK8ejDVzbRk+Br449Q37V6b0t7tUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}