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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '187020d39104f34ffd992ec0ab42cb76c903bdc0362268d6aa4cd3945c15e379' 
  AND token = 'Ay1Hv6/0MfsPv/fs/5zSE88rN3cCMeJMDJ+gAC5YzPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}