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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a7429e595b8c4bfbd2f3777de7a45a1d125cb016f54172c12534f0a083dbe7cf' 
  AND token = 'Ryb0i+41GZ/15yfyJa2+nAgDy2whAes+ne2tXIK1dOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}