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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2e664f6ca8d6c7cc64c86e45ecd58999bdb518d30ca8d63984502c5ee474d208' 
  AND token = 'PXEI0sZz1JyPtFX87npseF9z1loZaLOLO7lz7+l2lZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}